Reality TV star Ashley Cain shared his heartbreak when he learned that his daughter’s leukemia had returned despite five months of hospital treatment

Former soccer player and Ex On The Beach star revealed that seven-month-old baby Azaylia had to ring the bell to signal the end of her cancer treatment – but doctors then informed the “aggressive and rare” AML leukemia has come back

Cain, 30, wrote on Instagram that he and girlfriend Safiyya Vorajee Azaylia wanted to share their moment when he shared a video of staff lining the corridors to applaud her

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He wrote, “Today was supposed to be a day of undeniable happiness, however, it turned out like most days on this journey; a miracle that is blind with heartache!

“A few days ago we were told that Azaylia would ring the doorbell today and come home with us to continue the treatment 2 days a week on an outpatient basis 10 minutes before the moment we have been praying however for the past 5 months we have been Urgently informed that Azaylia’s leukemia had returned

“We broke down and canceled the celebration when we felt broken to the core and numb before we saw her beautiful face tell us the show must go on and then we realize how far our little girl is has come and how much she deserves this moment.She has fought against the odds, she has overcome every obstacle in her path and she has done everything with remarkable spirit and the biggest smile on her face!

“For the moment we are enjoying precious moments at home until we return to the hospital on Friday! Thank you for your support and please keep our beautiful daughter in your prayers!”

Ayzalia Diamond Cain was born in August 2020 and was diagnosed with cancer at the age of just two months in October last year

Announcing her diagnosis, Kain wrote on social media: “Yesterday I had to go through something no parent in the world should go through. The most exciting, terrifying, and heartbreaking experience I’ve ever had. I found that with my beautiful Daughter Azaylia Diamond Cain was diagnosed with a very rare and aggressive form of leukemia, which is associated with many complications

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“All who wish please say a prayer for my lovely brave little girl Azaylia who is in a fight for her life right now! Mom and Dad love you, Princess LETS GO CHAMP They can and you will beat this!”

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She has lived at Birmingham Children’s Hospital for five months and is undergoing chemotherapy and stem cell treatment

Earlier this month, on World Cancer Day, Cain highlighted the benefits of umbilical cord donations from new mothers to aid stem cell treatment

German customs officers found more than 16 tons of cocaine in containers that came to Hamburg from Paraguay, the authorities said on Wednesday.The Hamburg customs office described the find in the German port as the largest amount of cocaine seized in Europe and one of the most largest single seizures worldwide The drugs were found in a search in February 12 of five containers from Paraguay that had been classified as suspicious in a risk analysis by several European customs authorities, said the Hamburg office with

Dublin, February 24, 2021 (GLOBE NEWSWIRE) – The “Drug Discovery Outsourcing Market Size, Share & Trends Analysis Report by Workflow (Lead Identification & Candidate Optimization, Other), by Therapy Area (Oncology, Respiratory System), by Drug Type and Forecasts Segment, 2021-2028 “report has been added to ResearchAndMarketscom offering Global Drugs Outsourcing Market Size Expected to Reach $ 5.4 billion by 2028 with a CAGR of 74% over the forecast period Drugs discovery is a costly and lengthy process That Pharma Has – and biotech companies are forced to outsource their research activities to academic and private contract research organizations (CROs) Factors such as high R&D costs, best-seller patents expiring, and the need to accelerate the drug discovery process are likely to drive demand for drug discovery outsourcing in the coming years. Increasing cases of chronic diseases have forced companies to develop better drugs. Where companies are actively outsourced include oncology, cardiovascular disease and anti-infectives.In November 2020, AstraZeneca partnered with 9 of the leading oncology medical centers to advance research on some of the hardest-to-treat cancers, going clinical and not Fund clinical research proposals from members of this network The COVID-19 pandemic has put pharmaceutical companies in the spotlight It shows the value of drug discovery and developmentSeveral companies are proactive in the E Development of an effective vaccine to treat the disease involved Pfizer Inc and BioNTech SE received first approval for the vaccine after a global phase 3 study with a potential strain to fight the virus, many clinical trials are being abandoned while some are functional due to remote monitoring technologies The pandemic has put the pharmaceutical industry at the center, and that Outsourcing of drug discovery has become a key aspect of developing effective treatments for the virus, which is expected to increase market revenue for the next 2 years I.e a short-term boom after which it should regain its original growth curveHighlights of Drug Discovery Outsourcing Market report Lead Identification & Candidate Optimization Was the Dominant Workflow Segment of the Global Market in 2020, The segment will maintain its leading position throughout the forecast period as the optimization of & candidate for lead identification is one of the critical processes in drug discovery The oncology therapeutics segment is expected to record the fastest CAGR from 2021 to 2028 The small molecule drug types segment led the market in 2020 and is expected to experience the fastest growth rate over the forecast period, but this may change in the short term, with an emphasis on biologics, in terms of revenue sharing, North America is valued as the leading regional market during the forecast period, however, the Asia-Pacific region is valued as a result of governmental Alliance initiatives with the U.S. are expected to be the fastest growing regional market from 2021 through 2028 Pharmaceutical companies Main topics covered: Chapter 1 Methodology and scope11 Market segmentation & Scope12 Research methodology13 Information gathering14 Information or data analysis15 Market formulation & validation16 Model details17 List of secondary sources18 List of primary sources19 ObjectivesChapter 2 Summary21 Market outlook22 Segment outlook23 Prospective insightsChapter 3 market outlooks of CSSEANDSANDSCAPE trends 31 Industry Value Chain Analysis321 Reimbursement Framework33 Market Dynamics331 Market Driver Analysis332 Market Reluctance Analysis333 Industry Challenges34 Market Analysis Tools for Pharmaceutical Outsourcing341 Industry Analysis – Porter’s342 PESTEL Analysis343 Key Deals & Strategic Alliances Analysis344 Market Entry Strategies Workflow CHmAR-Outs-EstimatesANDSCAPE ent Dashboard42 Definitions and Scope43 Market Share of Drug Discovery Outsourcing, 2020 & 202844 Market Size & Forecasts and Trend Analysis, 2016 to 2028 for the Following441 Target Identification & Screening442 Target Validation & Functional Informatics443 Lead Identification & Workflow and Candidate Optimization for Active Substance Research5444 Pre-Marketing Workflow Therapeutic Area Estimates & Trend Analysis51 Segment Dashboard52 Definitions and Scope53 Drug Discovery Outsourcing Market Share, 2020 & 202854 Market Size & Forecasts and Trend Analysis, 2016 to 2028 for the following541 Respiratory System542 Pain & Anesthesia543 Anti-Circulatory Immunity543 Oncology544 Central Eematology-Gastric Infection51254 Dermatology 5413 Genitourinary System Chapter 6 Drug Discove Ry Outsourcing Market: Drug Type Estimates & Trend Analysis61 Segment Dashboard62 Definitions and Scope63 Drug Discovery Outsourcing Market Share, 2020 & 202864 Market Size & Forecasts & Trending Analysis, 2016-2028 for The Following641 Small Molecules642 Large Molecules (Biopharmaceuticals Outsourcing) Chapter 7 Market: Regional Estimates & Trend Analysis71 Regional Market Dashboard72 Regional Market Share Analysis, 2020 & 202873 Regional Market Share, 2020Chapter 8 Competitive Landscape81 Company Overview82 Financial Performance83 Product Benchmarking84 Strategic Initiatives Albany Molecular Research IncEVOTECLaboratory Corporation of America HoldingsGenScriptPPD IncCharles RiverWuXi AppTecMerck & Co, IncThermo Fisher Scientific IncDalton Pharma ServicesOncodesignJubilant BiosysDiscoverX CorporationQIAGEN For more information on this report, please visit https: // wwwResearch and Marketscom / r / pm3tsh CONTACT: CONTACT: ResearchAndMarketscom Laura Wood, Senior Press Manager press @ researchandmarketscom For ES.T Office Hours Call 1-917-300-0470 for US/ CAN toll free at 1-800-526-8630 For GMT office hours, call 353-1-416-8900

Jeffrey Court Inc The industry leader in decorative tile and stone today announced the creation of an employee benefit program designed to create a more sustainable way of collecting marketing resources while giving back to employees

Transformative Deal Could Open New Opportunities for Both CompaniesA Emerging Market Sponsored Commentary ORLANDO, Fla, Feb Sep. 24, 2021 (GLOBE NEWSWIRE) – Transformative This is the key word in a recent headline for today’s editorial feature on diversified health and wellness, beverage and natural products company BevCanna Enterprises Inc (CSE: BEV, Q: BVNNF, FSE: 7BC), who reported that they had announced their previously announced acquisition of Naturo Group Investments Inc (“Naturo”) You will forgive us for not bringing the news of the potential deal to your digital door, but we prefer closed deals to unfinished jobs in The EMR It’s a fascinating acquisition for a cannabis company in a market with Positioned with renewed affection for the industry, now adding Naturo’s innovative herbal mineral beverage and supplement brand TRACE, as well as significant manufacturing infrastructure and international distribution networks.The third paragraph of the press release should grab the attention of an astute investor as it has both successful sales and a now impressive presence in the beverage market confirmed Take a look: “The combination of these two up-and-coming industry leaders creates varied health and wellness Beverage and natural products company with assets of 55 million And while that glitzy $ 55 million should be a buzz, the long-term grabber for us is “a global, multi-channel sales network that is built on Growth is oriented “BevCanna’s own brands can now potentially benefit from an established sales network of over 3000 retail outlets use Naturo’s mineral beverage brand TRACE There is also a 40000 square meter ultra-modern beverage production facility, 315 hectares of farmland, a naturally alkaline spring water aquifer on site and of course the product suite of the plant-based beverage and supplement brand TRACE from Naturo, which also includes alkaline and sparkling water. For us, the big picture is not just two balances add up, but with regard to the merger: Which economies of scale contribute to margins and increase efficiency? And even better, how do the now shared sales channels generate greater product diversification, market share and sales? Because sometimes 1 1 = 3 information on the Emerging Markets Report: The Emerging Markets Report is owned and operated by Emerging Markets Consulting (EMC), a syndicate of investor relations consultants with many years of experience. Our network consists of stockbrokers, investment bankers, fund managers and institutions, who are actively looking for opportunities in the micro- and small-cap stock markets For more informative reports like this one, please log on to Emergingmarketsllccom / NewsletterPHP must read OTC Markets / SEC guidelines on stock promotion and investor protection https: / / wwwotcmarketscom / learn / Policy-on-Stock-Promotionhttps: // wwwotcmarketscom / learn / investorenschutzhttps: // wwwsekgov / news / press release / 2017-79https: // wwwsekgov / oiea / investoren-alarm-bullets / ia_promotions According to section 17 (b ) of the Securities Act of 1933, any person who uses the e-mail to post any publications or notices must Disclose, publish, or distribute a security that describes, receives in return for consideration, or is received directly or indirectly from an issuer, subscriber, or trader must fully disclose the nature of the consideration (i.e. cash, free trade shares, restricted stocks, stock options, warrants) and the specific amount of consideration.In this regard, EMC has received the following remuneration and / or has made an agreement to receive certain remuneration in the future, as described below We may have securities of the featured company buy before their securities are publicly traded, which we can later publicly sell before, during, or after our dissemination of the information, and earn a profit from it. EMC does not review or sponsor any medical claims for any of its client companies. EMC was founded by BevCanna Enterprises Inc At 350$ 000 paid for various marketing services including this report EMC does not independently review any content referenced in this editorial http: // Emergingmarketsllccom / DisclaimerPHP Emerging Markets Consulting, LLCFlorida Office390 North Orange Avenue Suite 2300Orlando, FL 32801Email: jamespainter @ emeringmarketsllccomWeb: wwwEmergingmarketsllccom

Calgary, Alberta and Isle of Man, Isle of Man – (Newsfile Corp – 24 February 2021) – Real Luck Group Ltd (TSXV: LUCK) (the “Company”) and its subsidiaries operating as “Luckbox” (“Real Luck Group” or “Group”), a provider of legal real money esports betting, are pleased to announce CEO Quentin Announce Martin’s intention to attend the following investor conferences: Proactive Proactive One2One Virtual Forum – Dec. February, 4 Gravitas Growth Conference – 4 March

The Northern Irish secretary said it was not credible for Stormont Treasury Secretary to say that the executive branch does not have the money for the program

NEW Veeam Backup & Replication v11 enables the most advanced data protection solution for cloud, virtual, physical and enterprise workloads

The Bank of Canada claims to be closely monitoring the country’s glowing real estate market

Virios Therapeutics, Inc (Nasdaq: VIRI), a clinical-stage biotechnology company focused on advancing novel antiviral therapies to treat diseases associated with virally induced or sustained immune responses, announced today that Greg Duncan, Chairman and Chief Executive Officer, at the H will present a company overview C. Wainwright Global Life Sciences Conference, 9 until 10 March 2021 takes place

NESS ZIONA, Israel, Feb. 24, 2021 (GLOBE NEWSWIRE) – Sol-Gel Technologies (NASDAQ: SLGL) (“Sol-Gel”), a clinical-stage dermatology company focused on the identification, development, and commercialization of Branded and Generic Topical Drugs for the Treatment of Skin Diseases, announced today that the company will provide an overview of the company and a business update at the following virtual investor conferences. Speakers at the Raymond James Institutional Investors Conference: Dr Alon Seri-Levy, CEO Date: 8:20 a.m. ET on Dec. March 2021 Access: Available for conference participants H.C. Wainwright Global Life Sciences Conference Speaker: Gilad Mamlok, Chief Financial Officer Date: Nov.-10 March 2021 Access: Available for conference participants on request. A webcast repetition of the presentation at HC. The Wainwright Life Sciences Conference will be available in the Investors / Events and Presentations section of the company’s website at www.Sol-Gelcom for 30 days About Sol-Gel Technologies Sol-Gel is a clinical-stage dermatology company focused on identifying, developing and marketing of branded and generic topical drugs focused on the treatment of skin diseases, Sol-Gel leverages its proprietary microencapsulation technology platform to develop Twyneo-Creme (benzoyl peroxide and tretinoin), which is being studied to treat acne vulgaris, and Epsolay®, which is being used to treat of Papulopustular Rosacea The Company’s pipeline also includes SGT-210, a topical early-stage epidermal growth factor receptor inhibitor, Erlotinib, which is being studied for the treatment of palmoplantar keratoderma, and preclinical assets Tapinarof and Roflumilast en at wwwSol-Gelcom For more information, please contact: Sol-Gel Contact: Gilad MamlokChief Financial Officer 972-8-9313433 Investor Contact: Michael Levitan Solebury Trout 1-646-378-2920mlevitan @ Soleburytroutcom Source: Sol-Gel Technologies Ltd

SPOKANE, wash, Feb 24, 2021 (GLOBE NEWSWIRE) – Avista Corp (NYSE: AVA) today reported net income that the Avista Corp. Shareholders of $ 129 $ 5 million, or $ 190 per diluted share for the December 31, 2020 fiscal year ended, compared to $ 197 0 million, or $ 297 per diluted share, for the December 31, 2019 fiscal year ended fourth Quarter 2020 will be allocated to Avista Corp Shareholders was $ 58.7 million or $ 085 per diluted share compared to $ 508 million or $ 076 per diluted share for the fourth quarter of 2019 “In the midst of this ongoing COVID-19 pandemic, thanks to the dedication and determination of our Employees Took Many Steps to Help Our Business Grow We have installed almost all of our smart meters across Washington to help our customers better manage their energy usage With the Rattlesnake Flat wind farm online, we are moving closer to Avista’s clean power goals, “said Avista President and CEO Dennis Vermillion.” As part of Avista’s longstanding commitment to corporate responsibility, we recently made our first set of improved commitments and disclosures Environmental, Social and Governance published, which can be found in the Corporate Responsibility section of the Avista website. Avista has been named one of the “Most Ethical Companies in the World” by Ethisphere for the second year running “In terms of results, earnings were Avista Utilities better than expected due to higher utility margins and lower income taxes, which was partly offset by higher operating costs “AEL&P’s results exceeded expectations due to higher sales volumes to private customers due to cooler weather than last year and lower operating costs due to COVID-19-be Operational Restrictions “We initiate our earnings forecast for 2021, 2022, and 2023 with consolidated ranges of $ 196 to $ 2 16 per diluted share in 2021, $ 218 to $ 2 38 per diluted share in 2022, and $ 242 to $ 2 62 per diluted share in Year 2023, ”Vermillion added. Summary Results: Avista CorpResults for the fourth quarter of 2020 and fiscal year ended December 31, 2020 (year-to-date) versus the respective periods in 2019 are shown in the following table (in thousands of dollars excluding data per share): Net Income Fourth Quarterly since the beginning of 2020, 2019, 2020, 2019, 2019 (loss) by business area: Avista Utilities 55680 USD 44891 USD 124810 USD 183977 USD AEL&P 3104 2633 8095 7458 Others (49) 3252 (3417) 5544 Overall Results of Avista Corp. Shareholders 58735 USD 50776 USD 129488 USD 196$ 979 Earnings (Loss) Per Diluted Share by Business Unit: Avista Utilities $ 081 $ 067 $ 183 $ 277 AEL&P 004 004 012 011 Other – 005 (005) 009 Total Earnings Per Diluted Share of Avista Corp. Shareholders $ 085 $ 076 $ 190 $ 297 Analysis of Consolidated Results 2020 The table below shows the change in net income of Avista Corp. Shareholders and diluted earnings per share for the fourth quarter and fiscal year ended Dec. December 31, 2020 compared to the same periods in 2019 and the various after-tax factors that led to such a change (in thousands of dollars excluding data per share): Year-to-date fourth quarter net income (a ) Earnings per share net profit (a) Earnings per share 2019 consolidated profit 50776 USD 0 USD76 $ 196979 $ 297 Changes in net earnings and diluted earnings per share: Avista Utilities Electric Utility Margin (including intra-group companies) (b) 3926 006 13948 020 Natural gas supply margin (including intra-group companies) (c) 3545 005 7.231 010 Other operating expenses (d) 3922 006 (7090) (010) Merger costs (e) – – 13293 019 depreciation (f) (2521) (004) (13853) (021) Interest expense (269) – (450) (001) Fee for the termination of the merger (g) – – (79254) (116) Others (h) 1111 002 775 001 Income tax at the effective tax rate (i) 1075 002 6.233 009 Dilution of the result n / a (003) n / a (005) Total Avista Utilities 10789 014 (59, 167) (094) AEL&P result 471 – 637 001 result of other companies (j) (3301) (005) (8,961) (014) 2020 consolidated profit $ 58$ 735 $ 085 $ 129488 $ 190 (a) The tax implications of each line item were determined with Avista Corp.statutory tax rate (federal and state combined) of 2305 percent (b) The electricity supply margin (operating income minus resource costs) increased in the fourth quarter and for the full year and was mainly influenced by the following: General rate increase in Washington with effect from 1 April 2020 Customer growth contributed to additional electricity revenues in retail A decrease in net utility costs caused by a decrease in electricity purchase prices and thermal fuel costs for full year 2020 compared to 2019.For full year 2020, we booked a pre-tax benefit of $ 6 million under the Energy Recovery Mechanism (ERM) compared to A full year 2019 pre-tax benefit of $ 4.4 millionFor the full year there was a 3 percent decrease in total load, composed of a 6 percent decrease in commercial use and a 9 percent decrease in industry, which was partially offset by a 3 percent increase in housing costs, mainly due to COVID-19, part of the commercial and all industrial loads are not covered by our decoupling mechanisms (c) the natural gas supply margin (operating income minus resource costs) increased in the fourth quarter l and in full year 2020 and was mainly influenced by the following: General rate increases in Oregon, effective January 15, 2020 and Washington, effective January 1, 2020 April 2020 Customer growth contributed to additional natural gas retail revenue (d) Other operating expenses increased for full year 2020 mainly due to increased operating and maintenance costs for generation and distribution There was also a rejection from the Washington Commission for the cost of replacement electricity during an unplanned outage at the Colstrip generation facility in 2018 and a provision for the Colstrip Community Transition Fund related to the completion of our Washington general tariff cases in 2019 in the first quarter of 2020.These increases were partially offset by a $ 7 million donation in the Year 2019 In the fourth quarter, earnings benefited mainly from the deferral of the additional expense for bad debts (e) The costs of the merger transaction are related to the planned (now completed) takeover by Hydro One (f) The depreciation rose around of utility additions The current year also included an item in the second quarter of 2020 where we were able to use $ 10 million ($ 8) in electrical tax benefits to offset costs related to the Colstrip Units 3 & 4 amortization accelerated due to Washington settlement This amount was recorded as a one-time increase in amortization expense in Q2 2020 and offset by a decrease in income tax expense in Q2 2019, a similar item of $ 6 was posted for Idaho4 Million (US $ 5) million in taxes) (g) As a result of the termination of the proposed (now terminated) business combination, Hydro One paid Avista Corp. a $ 103 million termination fee in January 2019 (h) Other for full-year 2020 was an increase in earnings mainly driven by a decline in non-service pensions and the increase in other income was partly driven by an increase in property taxes balanced (i) Our effective tax rate was 52 percent for 2020 compared to 138 percent for 2019 The decrease in the tax rate was mainly due to the offsetting of deferred income taxes against Colstrip’s accelerated amortization recorded in Q2 2020 and 2019, which is related to the Effective Tax Rates This was $ 84 million in 2020 compared to $ 51 million in 2019 (j) In the current year, our other businesses’ earnings declined mainly due to the sale of METALfx in 2019 financial metrics for non general Recognized Accounting Policies (Non-GAAP) The tables above and below show the Electric Utility Margin and Natural Gas Distribution Margin, two financial measures that are considered “Non-GAAP Financial Measures.” In general, a non-GAAP financial measure is a numeric measure for a company’s financial performance, financial condition, or cash flows that excludes (or includes) amounts included (or excluded) in the most directly comparable measure calculated and presented in accordance with GAAP, which is the benefit margin Operating income trades The presentation of the electricity supply margin and the natural gas supply margin is intended to improve understanding of the operating performance. We apply these measures internally and we believe that they provide investors with useful information for their analysis of how changes in loads (due to weather conditions, economic or other n terms), rates, delivery costs and other factors affect our results of operations Changes in loads and costs of electricity and natural gas supplies are generally deferred and reclaimed from customers through regulatory accounting mechanisms.As a result, the analysis of the supply margin generally includes most of the Changes in sales resulting from these regulatory mechanisms. We show the margin for electricity and natural gas suppliers for Avista Utilities separately, as each company has different cost sources, cost recovery mechanisms and jurisdictions We therefore consider a separate analysis to be advantageous These measures do not replace the operating income of the utility companies determined according to GAAP as an indicator of operating performance The reconciliation of operating income to the utility margin is shown below The following table shows the operating income, resource costs and the resulting utility margin (before and after taxes) from Avista Utilities for the three and twelve months ending on 31 December 31st (in thousands of US dollars) listed: Operating Income ResourceCosts UtilityMargin (pre-tax) IncomeTaxes (a) UtilityMargin (after-tax) For the three months ended December 31, 2020: Electric $ 242131 $ 71445 $ 170686 $ 39$ 343 131343 natural gas 149270 73672 75598 17424 58174 Less: Intracompany (23042) (23042) — Total $ 368359 $ 122075 $ 246284 $ 56767 $ 189517 For the three months ended December 31, 2019: Electric 243670 $ 78086 $ 165584 $ 38167 $ 127417 natural gas 144523 73531 70992 16363 54629 Less: Intracompany (34761) (34761) — Total $ 353432 $ 116856 $ 236576 $ 54$ 530 182046 For the twelve months ending December 31, 2020: Electric 927540 $ 264595 $ 662945 $ 152$ 809 510136 natural gas 435882 217902 217980 50244 167736 fewer: Intracompany (85954) (85954) – – – Total 1277468 $ 396$ 543 880$ 925 207 31, 2019: Electric $ 962048 $ 317$ 229 644819 $ 148631 $ 496188 natural gas 447232 238649 208583 48078 160505 Less: Intracompany (113407) (113407) — Total $ 1295$ 873 442471 $ 853402 $ 196statutory tax rate (federal and state together) of 2305 percent Liquidity and capital resources Liquidity We have a committed credit line of 400 million USD expiring in April 2022 as of Dec. As of December 31, 2020, we had $ 2704 million of liquidity available under this line of credit AEL&P had $ 24 million of liquidity available under its committed line of credit, which expires in November 2024 In 2020, we issued common stock for approximately $ 72 million in net proceeds. 2021 Liquidity Transactions In 2021, we are expected to incur long-term debt of approximately US $ 72 million 120 million USD and equity of 75 million Issue USD to fund planned investments Investments and other investments Avista Utilities invested 397 million in 2020 USD and AEL&P’s investments of 7 million We expect investments of USD 415 million in 2021 USD at Avista Utilities and 7 million USD at AEL&P Additionally, we expect to invest approximately $ 15 million in our other businesses in 2021, mainly related to unregulated investment opportunities and economic development projects in our service area 2021 Earnings Forecast and Outlook Avista Corp. initiates its earnings guidance for 2021, 2022, and 2023 with consolidated ranges of $ 196 to $ 2 16 per diluted share in 2021, $ 218 to $ 2 38 per diluted share in 2022, and $ 242 to $ 2 62 per diluted share in 2023 ours Guidelines assume timely and appropriate interest rate relief in our countries.We had a regulatory backlog in 2020 and expect this to continue until the end of 2022 as we continue to invest in utility infrastructure and filing in our jurisdictions in Washington and Idaho Delayed In October 2020, we filed general tariff cases in Washington, and in March we filed a general tariff for natural gas in Oregon (with new tariffs starting January 16, 2021) In addition, we filed general tariff cases in Idaho in January 2021 We assume that these cases will lead to an interest rate relief in 2021 and the Will reduce regulatory lag Going forward, we will continue our efforts to reduce the regulatory lag and align our returns more closely with the revenues approved by 2023.We expect growth to return to 4 to 6 percent after 2023 Our earnings forecast for 2021 reflects non-reimbursed structural costs, which are expected to increase the return on equity by approx 70 basis points, as well as the regulatory delay that is expected to reduce the return on equity by approx 100 basis points. This leads to an expected return on equity for Avista Utilities of approx 77 percent in 2021 We expect Avista Utilities to contribute in the range of $ 1.93 to $ 2.07 per diluted share for 2021. In the middle of our Avista Utilities guide, there are no costs or benefits under the ERM, our current expectation for the WKM is an advantage position within the 75 percent customer / 25 percent company sharing band, which is expected to contribute $ 0.50 per diluted share In 2021, we expect AEL&P to contribute in the range of USD08-08 $ 011 per diluted share We expect the other companies to lose $ 0.05 to $ 002 per diluted share We expect higher costs related to exploring strategic business opportunities in 2021 Our outlook for Avista Utilities and AEL&P assumes normal rainfall, temperatures, among other things , Hydropower generation and other operating conditions for the rest of the year Our guidelines do not consider the effects of unusual or non-recurring elements until the effects are known and certain.We cannot predict the duration and severity of the global COVID-19 pandemic, the longer and more severe the economic restraints and business disruptions, the greater they will be Our Business, Results of Operations, Financial Condition, and Cash Flow Impact: We will host a conference call with financial analysts and investors on February 24, 2021 at 10:30 a.m. ET to discuss this press release and the call is at (855) 806 -8606, confirmation number: 1075438 # available A simultaneous webcast of the call will be available on our website at Avistacorpcom.A replay of the conference call will be available through March 03, 2021. Call (855) 859-2056, confirmation number 1075438 # to listen to the replay from Avista Corp. is an energy company involved in the generation, transmission and distribution of energy, as well as other energy-related businesses. Avista Utilities is our division, the 400000 customers powered and 367000 customers supplied with natural gas Our service area covers 30000 square miles in east Washington, north Idaho, and parts of southern and eastern Oregon with a population of 17 million AERC is an Avista subsidiary that operates through its subsidiary AEL&P 1710,000 customers in the city and borough of Juneau, Alaska. Our stock trades under the ticker symbol “AVA” For more information on Avista, visit wwwAvistacorpcom Avista Corp. and Avista Corp Logo are trademarks of Avista Corporation. This press release contains forward-looking statements, including statements about our current expectations for future financial performance and cash flows, investments, financing plans, our current plans or goals for future operations, and other factors that may affect the company in the future Such statements are subject to a number of risks, uncertainties and other factors, most of which are beyond our control and many of which could have a material impact on our business, results of operations, financial condition, or cash flow and could cause actual results to differ materially The following factors could cause actual results to differ materially from those anticipated in the forward-looking statements: State and federal regulatory risk decisions or, consequently, v pending court decisions that affect our ability to reimburse costs and obtain a reasonable return, including, but not limited to, non-approval or delay in reclaiming capital investments, operating costs, raw material costs, interest rate swap derivatives, ordering refunds to customers and discretion in the allowable return on investment; loss of regulatory accounting, which could require depreciation of regulatory assets and loss of regulatory deferral and recovery mechanisms; Operational risk pandemics (including the current COVID-19 pandemic) that could disrupt our business and the global, national and local economies, resulting in a decline in customer demand, a deterioration in our customers’ creditworthiness, an increase in the cost of operations and capital, Labor shortages, delays in capital projects, disruptions in supply chains and disruptions, weaknesses and volatilities in the capital markets. In addition, one of these factors could, among other things, negatively affect our liquidity and restrict our access to capital Forest fires launched by Avista Corp. Equipment or facilities can cause significant loss of life and property and Avista Corp. thereby cause serious operational and financial damage and our customers; Severe weather or natural disasters, including but not limited to avalanches, wind storms, forest fires, earthquakes, snow and ice storms, which may disrupt power generation, transmission and distribution, as well as the availability and cost of fuel, materials and equipment supplies and support services; Explosions, fires, accidents, mechanical failures, or other incidents that may affect assets and disrupt the operation of our generating facilities, transmission, power and natural gas distribution systems, or other operations, and potentially requiring the purchase of backup power or costing the repair of our facilities. These incidents may may also lead to public injury or property damage Power outages or interruptions in interconnected transmission networks (regional electricity network); Terrorist attacks, cyberattacks or other malicious activity that disrupts or could damage our utilities or the national or regional economy in general, including the effects of terrorism, cyber attacks, ransomware or vandalism that damage or disrupt information technology systems; Problems with the workforce, including changes in collective agreements, strikes, work stoppages, loss of key management personnel, availability of workers in a variety of skill areas, and our ability to hire and retain employees; Changes in the availability and price of purchased electricity, fuel and natural gas, as well as transmission capacity; rising insurance costs, more restrictive terms and conditions and our ability to take out insurance; Delays or changes in construction costs and / or our ability to obtain necessary permits and materials for current or future facilities; Increasing health care and insurance costs for our employees and retirees; Construction of buildings, billboards, towers or other structures by third parties within the scope of our rights of way or the placement of fuel tanks in the immediate vicinity of our transformers or other equipment, including superstructures on natural gas distribution lines; the loss of key suppliers of materials or services or other supply chain disruptions; adverse effects on our Alaska Electricity Company (AEL&P) that could result from prolonged downtime of its hydropower resources or its inability to deliver power due to disconnection to other power grids and the availability or cost of backup electricity (diesel); Changes in river regulation or the operation of hydropower plants that we do not own, which could affect our downstream hydropower plants; Change in the use, availability or abundance of water resources and / or rights necessary for the operation of our hydropower plants; Cyber ​​and technology risk Cyber ​​attacks on the operating systems used to operate our electricity generation, transmission and distribution facilities and our natural gas distribution facilities, as well as cyber attacks on such systems of other energy companies with which we are affiliated that damage or may damage facilities or Destroying systems or disrupting operations for a long period of time, resulting in liabilities and costs; Cyber ​​attacks on the administrative systems used to manage our business, including customer billing and customer service, accounting, communications, compliance and other administrative functions, as well as cyber attacks on such systems of our suppliers and other companies with whom we do business that could disrupt business operations, lead to the release of private information and the incurrence of liabilities and costs; Changes in costs that affect our ability to effectively implement new information technology systems or operate and maintain current production technologies; Changes in technology that may obsolete some of the current technology we use or introduce new cybersecurity risks; inadequate technological capabilities that could prevent our information systems from being developed, modified or maintained; Strategic risk growth or decline in our customer base due to new uses of our services or decline in existing services, including but not limited to the impact of the trend towards distributed generation at customer locations; the potential impact of negative publicity regarding our business practices, whether true or not, that could damage our reputation and lead to litigation or a decline in our common stock price; Changes in our strategic business plans that could be influenced by any or all of the above factors, including entering new business areas and / or exiting existing business areas and the scope of our business development efforts when potential future business is uncertain; Wholesale and retail competition, including alternative energy sources, growth in proprietary energy resource technologies that displace energy from utility companies or can be repurchased to energy providers, and alternative energy providers and supply arrangements; Entering or growing unregulated activities can increase the volatility of profits the risk of municipalization or other forms of coverage area reduction; External Mandates Risk changes in environmental laws, regulations, decisions and policies, including the current and potential costs of environmental remediation and our compliance with these matters; the potential impact of any federal, state or local initiative, law, or regulation, including the potential impact on our generating resources, bans or restrictions on new or existing services, or restrictions on greenhouse gas emissions to mitigate global climate change concerns; Political pressure or regulatory practices that could restrict our distribution systems through an accelerated introduction of decentralized generation or electrically operated transport or our energy supply sources or cause additional costs, e.g. B. Campaigns to cease power generation from fossil fuels and oppose other thermal energy generation, wind turbines or hydroelectric plants; Failure to identify changes in legislation, taxes, and regulatory issues that could adversely or beneficial to our overall business; Policy and / or law changes in various regulated areas including, but not limited to, environmental regulations, health regulations and import / export regulations; Financial weather conditions that affect both energy demand and electricity generation capacity, including the effects of precipitation and temperature on hydropower resources, the effects of wind patterns on wind power, weather sensitive customer demand, and similar effects on supply and demand in wholesale energy markets; our ability to obtain funding through the issuance of debt and / or equity securities that could be affected by various factors including our credit ratings, interest rates, other capital market conditions and global economic conditions; Changes in interest rates that affect the cost of borrowing, our ability to effectively hedge interest rates on anticipated debt issuance, floating rate loans and the extent to which we get interest costs back through customer-levied retail rates; Changes in actuarial assumptions, interest rates, and the actual return on plan assets for our pension and other pension plans that could affect future funding obligations, pension and other pension expenses and related liabilities; the outcome of legal proceedings and other contingent liabilities; economic conditions in our service sectors, including the impact of the economy on customer demand for utilities; National economic conditions can affect the valuation of our unregulated portfolio companies Declining energy demand in connection with energy efficiency of customers, savings measures and / or increased decentralized generation; Changes in long-term climate and weather can, among other things, significantly affect customer demand, the volume and timing of the electricity flows required for hydropower generation, as well as the costs of generation, transmission and distribution. Increased or new risks can arise from severe weather or natural disasters, including forest fires Industry and geographic concentrations that could increase our credit risk as counterparties, suppliers and customers are similarly affected by changing conditions; Deterioration in our customers’ creditworthiness; Volatility and illiquidity of energy commodity risk in wholesale energy markets, including stock exchanges, availability of willing buyers and sellers, changes in wholesale energy prices that could affect operating results, cash needs to purchase electricity and natural gas, value received for wholesale sales, required collateral from us from individual counterparties and / or exchanges in wholesale energy transactions and credit risk to us from such transactions and the market value of derivative assets and liabilities; Failure or non-performance by parties from whom we buy and / or sell capacity or energy; potential environmental regulations or legal disputes affecting our ability to use or obsolescence of our electrical utility resources; Explosions, fires, accidents, burst pipes or other incidents that could reduce the energy supply to our facilities or our surrounding area, which could result in a shortage of goods in the market that could increase the cost of replacement goods from other sources; Compliance Risk changes in laws, regulations, decisions and guidelines at the federal, state or local level that can have a significant impact on our electricity and gas operations as well as our operating costs; and the ability to meet the terms of the licenses and permits for our hydropower or heat generation facilities at a cost effective level.For more information on these and other important factors, please see our Form 10-K for 2020 The forward-looking statements contained in this press release speak only as of the date of this Press Release We undertake no obligation to update any forward-looking statements or statements to reflect events or circumstances that occur after the date on which these statements were made or to reflect the occurrence of unexpected events. From time to time, new risks, uncertainties and others may arise Factors, and management cannot predict all of these factors nor assess the impact each of these factors will have on our business or the magnitude of any such factor. The combination of factors could cause actual results to be materially varied results contained in forward-looking statements differ. To unsubscribe from distributing Avista news releases, please send a reply to Lena at funston @ avistacorpcom Issued By: Avista Corporation Contact: Media: Laurine Jue (509) 495-2510 Laurinejue @ avistacorpcomInvestors: John Wilcox ( 509) 495-4171 Johnwilcox @ avistacorpcomAvista 24/7 Media Access (509) 495-4174

ALPHARETTA, Ga, Feb 24, 2021 (GLOBE NEWSWIRE) – Clearside Biomedical, Inc (NASDAQ: CLSD), a biopharmaceutical company dedicated to developing and delivering therapies that restore and preserve vision in people with serious eye diseases, today announced that it announced its fourth quarter and full year 2020 financial results on Wednesday, the 10th Management will host a webcast and conference call at 4:30 p.m. Eastern time to discuss the results and provide a company update. The live and archived webcast can be viewed on the Clearside website at on March 23, 2021 after the end of the financial markets Investors Section: Events and Presentations On Access You can access the live call by dialing (844) 263-8310 (Domestic) or (213) 358-0959 (International) and entering conference code 5286349. An archive of the webcast will be three Be available for months through Clearside Biomedical Clearside Biomedical, Inc is a biopharmaceutical company dedicated to developing and delivering treatments that restore and preserve vision in people with serious eye diseases Clearside developed the SCS Microinjector® targets the suprachoroidal space (SCS®) and provides unique access to the macula The company’s SCS injection platform is an inherently flexible, non-surgical procedure in the office that allows targeted delivery to the disease site and work with established and new formulations of drugs as well as future therapeutic innovations For more information, visit wwwclearsidebiocom Investor and Media Contacts: Jenny Kobin Remy Bernarda ir @ clearsidebiocom (678) 430-8206 Source: Clearside Biomedical, Inc

Key companies in the home nursing and home nursing market include Genesis Healthcare; Kaiser Permanente; Brookdale Senior Living; Kindred Healthcare and The Ensign Group, IncNew York, February 24, 2021 (GLOBE NEWSWIRE) – Reportlinkercom Announces the Release of the Report “Home Health Care and Residential Nursing Care Services – Global Market Report 2021: COVID 19 Impact And Recovery By 2030” – https: // wwwreportlinkercom / p06027727 / ? utm_source = GNW The global home care and home care market is projected to grow from $ 95756 billion in 2020 to $ 100732 billion in 2021 with an average annual growth rate (CAGR) of 52%, growth is mainly due to companies reorganized their operations and recovered from the effects of COVID-19, which had previously resulted in restrictive containment measures that included social distancing, remote working and the cessation of commercial activities that resulted in operational challenges, the market is projected to reach $ 1,273 billion in 2025, with an annual growth rate of 6? The Home Care and Home Care Market consists of sales of Home Health and Home Care Services and Related Goods by corporations (organizations, sole proprietorships, and partners communities) that provide home nursing and home nursing, including personal services and counseling services, occupational therapy, recreational home services, social and nutritional services.The home nursing and home nursing market is divided into home nursing providers Care facilities; Orphanages & group houses; Western Europe was the largest region in the global home care and home care market, accounting for 43% of the market in 2020North America was the second largest region with a 33% share of the global home care and home care market, Africa was the smallest region in the global Home Nursing and Home Nursing MarketThe Nursing Industry Deploys Big Data Technologies to Monitor Patients’ Health and Deliver Appropriate CareBig data is large amounts of data that can be analyzed to generate insights and make decisionsBig data enables the Care providers can access a significant amount of data that health professionals can use to identify future health risks and suggest appropriate remedial action, and home care providers can also use this data to identify irregularities in the treatment of Pa Identify patients and improve treatment effectiveness For example, MJHS, a leading provider of home care, palliative care and hospice in the United States, has introduced eCaring, a big data technology solution to monitor a patient’s health and behavior every hour Tracking individual patient health outcomes The care market is expected to be limited by a shortage of trained doctors, counselors, nurses, and nurses in developed and developing countries. Developing countries face high health care shortages as the demand for care increases, for example there was According to the World Health Organization (WHO), a shortage of around 43 million global health workers, including nurses and healthcare workers, as of 2018. Developed countries are also experiencing a similar crisis, according to AAMC’s report, the US is currently facing a man gel faced by doctors, especially general practitioners According to the World Bank, the country has only 25 doctors per 1000 people, mainly due to the lack of proper skills and the lack of training and work experience among the candidates, the shortage of medical staff is likely to affect the future Further restricting care market Access to health services in developing countries is expected to improve and drive the care market in these regions Effective implementation of health plans is the main reason for improving access to health care in many developing countries such as India, China and Latin American countries, some country-specific health reforms that Should improve access to health care, include China’s basic urban insurance and health insurance systems for rural cooperatives, Brazil’s unified health system and Mexico’s national health insurance ersicherung Improving access to health care should have a positive impact on the growth of the care market Read the full report: https: // wwwreportlinkercom / p06027727 /? utm_source = GNWAbout ReportlinkerReportLinker is an award-winning research solution Reportlinker finds and organizes the latest industry data so you can get all the research you need – instantly in one place __________________________ CONTACT: Clare: clare @ reportlinkercom US: (339) -368-6001 Intl: 1 339-368- 6001

Dublin, February 24, 2021 (GLOBE NEWSWIRE) – The report, “Peanut Butter Market: Global Industry Trends, Share, Size, Growth, Opportunities, and Forecast 2021-2026” has been added to ResearchAndMarketscom offering the global peanut butter market reached a value of 3 US $ 4 Billion in 2020 Due to Market Drivers, Global Peanut Butter Market Will Show Moderate Growth in 2021-2026Peanuts are a major crop grown worldwide and used commercially to make oil, butter, flour, confectionery, and snack products among them is peanut butter One of the most widely consumed food spreads and is made by grinding and dry roasting peanuts.It is a high energy product that is usually marketed as a substitute for milk butter.In addition to energy, it also provides fiber, proteins and unsaturated fats, as well as a range of micronutrients such as magnesium , Zinc, potassium and vitamin E. Because of this nutritional profile, it is used to make a variety of food products including salads, brownies, rolls, cakes, frosting, cornbreads and chocolates.With the obesity rate rising, consumers around the world have started to opt for healthier breakfast and snack options, for example in the UK it is expected that peanut butter overtakes the sales of sweet spreads like jam as they are being targeted by Public Health England (PHE) as part of the Sugar Reduction Plan under that program, the PHE aims to reduce the total amount of sugar in the foods consumed by children aside from that Due to increasing competition in the global market, manufacturers have put innovative marketing strategies in place to reach a wider consumer base.This is why Hormel Foods, a US-based food company, launched a new advertising campaign for its peanut butter in 2018 Brand Skippy Introduced Key Questions Answered In This Report1 What was the size of the global peanut butter market in 2019? 2 What is the growth rate of the peanut butter market? 3 What is the outlook for the peanut butter market over the next five years (2020-2025)? 4 What Are the Key Global Peanut Butter Market Drivers? 5 What are the main trends in the peanut butter industry? 6 Who are the leading players in the peanut butter industry? 7 What is the largest regional peanut butter market? 8 What is the dominant sales channel for peanut butter? 9 How is the peanut butter market broken down by product type? 10 What is the impact of COVID-19 on the global peanut butter market? Main topics covered: 1 Foreword2 Scope and methodology21 Objectives of the study22 Stakeholder23 Data sources24 Market estimate25 Forecast method3 Summary4 ​​Introduction41 Overview42 Key Industry Trends5 Global Sweet Spreads Industry51 Market Overview52 Market Performance53 Market Breakdown by Regions54 Market Breakdown by Product Type55 Market Forecast6 Global Peanut Butter Industry61 Market Breakdown by Region62. Market Performance622 Volume Trends -63 Market breakdown by sales channel67 Market forecast68 Price analysis69 SWOT analysis610 Value chain analysis611 Five forces analysis by Porter612 Main market drivers and success factors7 Peanut butter market: performance of the key regions8 Peanut butter market: breakdown by product type81 Crunchy peanut butter markets82 Smooth peanut butter markets by supermarket chain93 Distribution stores992 Online stores94 Other10 Competitive landscape101 Market structure102 Main players’ market share11 Peanut butter manufacturing process111 Product overview112 Detailed process flow113 Different types of unit operations involved114 Mass balance and raw material requirements12 Project details, requirements and costs121 Land requirements and expenses122 Construction requirements and expenses123 Plant layout124 Expenditures125 Machine pictures and requirements126 Raw material requirements and packaging125 Machine images and requirements126 Raw material requirements and packaging Transport requirements and expenditures1210 Supply requirements and expenditures1211 Personnel requirements and expenditures1212 Other capital investments13 Loans and financial support14 Project economics141 Project capital costs142 Techno-economic parameters143 Product prices and margins at different levels of the supply chain144 Taxes and depreciation145 Income forecasts146 Expenditure projections147 Financial analysis148 Ge winnanalyse15 Key Player Profiles Further information on this report can be found at https: // wwwResearch und Märktecom / r / jswpi6 CONTACT: CONTACT: ResearchAndMarketscom Laura Wood, Senior Press Manager press @ researchandmarketscom For ES.T Office Hours Call 1-917-300-0470 for US/ CAN toll free at 1-800-526-8630 For GMT office hours, call 353-1-416-8900

Ashley Cain

World News – UK – Ashley Cain, the star of ‘Ex On The Beach’, is broken when daughter’s leukemia returns